E3 Studio is E3's development environment. With it, users can create and maintain Domains, projects, and libraries.

To start an application in E3 Studio, select it on Windows Start menu or double-click the icon created on Windows Desktop Area during installation.

A protection device must be connected to the correct I/O port, in case of a local edition, or this machine must be on the same local network that another one with an E3 Server already installed, and with a protection device available.