Usually, a device must communicate with this Driver though a TCP/IP connection using MLLP (Minimum Lower Layer Protocol). A device can connect to the IP address where this Driver is executing or receive a connection from this Driver.

In case this Driver performs a connection, users must inform the IP address and the destination TCP/IP port on the Ethernet tab of this Driver's configuration window, in the Main IP and Port options, respectively. If this Driver receives a connection, users must inform the TCP/IP port where this Driver receives that connection in the Listen for Connections on port option.

Regardless of the type of TCP/IP connection, after establishing a connection the device must send the messages, which are responded automatically with an HL7 ACK-type message by this Driver. Usually, devices have a configuration informing how many times a message is retried if an ACK message is not correctly received inside a specified time-out, which is also configurable by the device. After reaching that number of retries without receiving a successful message, the message is then discarded by the device.